{"id":1307,"date":"2015-09-30T14:27:47","date_gmt":"2015-09-30T13:27:47","guid":{"rendered":"http:\/\/www.bacchus-fp7.eu\/?page_id=1307"},"modified":"2017-03-31T15:55:34","modified_gmt":"2017-03-31T14:55:34","slug":"bacchus-publications","status":"publish","type":"page","link":"http:\/\/www.eurofir.org\/bacchus\/bacchus-publications\/","title":{"rendered":"BACCHUS Publications"},"content":{"rendered":"<table class=\"no_border\" style=\"border: 0px dotted #969696;margin-bottom: 10px;width: 630px\" border=\"0\" cellspacing=\"1\" cellpadding=\"1\">\n<tbody>\n<tr>\n<td><a href=\"\/wp-content\/uploads\/sites\/5\/2016\/10\/Bacchus-Gonzalez16.png\"><img loading=\"lazy\" class=\"alignleft wp-image-2119\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/10\/Bacchus-Gonzalez16.png\" width=\"150\" height=\"99\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\"><br \/>\nCell Systems to Investigate the Impact of Polyphenols on Cardiovascular Health<\/span><\/h3>\n<p>Charlotte Grootaert and colleagues from Ghent (BE) and Istanbul Technical Universities (TR) have reviewed the literature concerning cell culture models for polyphenols and cardiovascular disease research &#8230;\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/cell-systems-to-investigate-the-impact-of-polyphenols-on-cardiovascular-health\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"\/wp-content\/uploads\/sites\/5\/2016\/10\/BacchusGrootaert17.png\"><img loading=\"lazy\" class=\"alignleft wp-image-2119\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/10\/BacchusGrootaert17.png\" width=\"150\" height=\"99\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Identifying the limits for ellagic acid bioavailability: A crossover pharmacokinetic study in healthy volunteers after consumption of pomegranate extracts\u00a0<\/span><\/h3>\n<p>Antonio Gonz\u00e1lez-Sarr\u00edas and colleagues from CEBAS-CSIC and the Catholic University of San Antonio(ES) have examined factors contributing to ellagic acid bioavailability in order to evaluate whether this can be improved &#8230;\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/identifying-the-limits-for-ellagic-acid-bioavailability-a-crossover-pharmacokinetic-study-in-healthy-volunteers-after-consumption-of-pomegranate-extracts\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td><a href=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/Kamigolu-Bacchus15.png\"><img loading=\"lazy\" class=\"alignleft wp-image-2119\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/Kamigolu-Bacchus15.png\" width=\"150\" height=\"99\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Anthocyanin Absorption and Metabolism by Human Intestinal Caco-2 Cells\u2014A Review<\/span><\/h3>\n<p>Researchers at Ghent University (BE) have reviewed the literature describing the Caco-2 cell models for testing the bioactive properties of anthocyanins and their beneficial health effects in humans &#8230;\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/anthocyanin-absorption-and-metabolism-by-human-intestinal-caco-2-cells-a-review\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/time_course_production_urolithins_ea_human_gut_microbia\/\"><img loading=\"lazy\" class=\"alignleft wp-image-2085\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/rasberries.png\" alt=\"rasberries\" width=\"150\" height=\"113\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Time Course Production of Urolithins from Ellagic acid by Human Gut Microbiota<\/span><\/h3>\n<p>Garcia-Villalba and colleagues from CEBAS-CSIC (ES) have conducted a study using detailed experiments <em>in vitro<\/em> and <em>in vivo <\/em>to identify the intermediary and final catabolites of ellagic acid in the human gut &#8230;\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/time_course_production_urolithins_ea_human_gut_microbia\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/potent-inhibition-of-vegfr-2-activation-by-tight-binding-of-green-tea-epigallocatechin-gallate-and-apple-procyanidins-to-vegf-relevance-to-angiogenesis\/\"><img loading=\"lazy\" class=\"alignleft wp-image-2083\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/green-tea.png\" width=\"150\" height=\"100\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Potent inhibition of VEGFR-2 activation by tight binding of green tea epigallocatechin gallate and apple procyanidins to VEGF: Relevance to angiogenesis<\/span><\/h3>\n<p>Christina W. A. Moyle and colleagues from the Institute of Food Research (IFR, UK) have demonstrate for the first time that VEGF is a key molecular target for specific polyphenols found in tea, apples and &#8230;\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/potent-inhibition-of-vegfr-2-activation-by-tight-binding-of-green-tea-epigallocatechin-gallate-and-apple-procyanidins-to-vegf-relevance-to-angiogenesis\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/interindividual-variability-in-the-human-metabolism-of-ellagic-acid-contribution-of-gordonibacter-to-urolithin-production\/\"><img loading=\"lazy\" class=\"alignleft wp-image-2084\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/pomegranate.png\" width=\"150\" height=\"100\" \/><\/a><\/td>\n<td>\n<h3 style=\"text-align: left\"><span style=\"color: #339966\">Interindividual variability in the human metabolism of ellagic acid: Contribution of Gordonibacter to urolithin production<\/span><\/h3>\n<p>Maria Romo-Vaquero and colleagues from the CEBAS-CSIC (ES) have examined the role of <em>Gordonibacter <\/em>and other human gut bacteria in human health &#8230; <a href=\"http:\/\/www.bacchus-fp7.eu\/interindividual-variability-in-the-human-metabolism-of-ellagic-acid-contribution-of-gordonibacter-to-urolithin-production\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/biological-significance-of-urolithins-the-gut-microbial-ellagic-acid-derived-metabolites-the-evidence-so-far\/\"><img loading=\"lazy\" class=\"alignleft size-full wp-image-2074\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/Bacchus-Biological-significance-of-urolithins.png\" alt=\"Bacchus-Biological significance of urolithins\" width=\"150\" height=\"100\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Biological Significance of Urolithins, the Gut Microbial Ellagic Acid-Derived Metabolites: The Evidence So Far<\/span><\/h3>\n<p>Juan Carlos Esp\u00edn and colleagues from CEBAS-CSIC (ES) have reviewed literature describing urolithin metabolites production by gut microbiota, their absorption, tissue distribution and pharmacokinetics, and &#8230; <a href=\"http:\/\/www.bacchus-fp7.eu\/biological-significance-of-urolithins-the-gut-microbial-ellagic-acid-derived-metabolites-the-evidence-so-far\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/ellagic-acid-metabolism-by-human-gut-microbiota-consistent-observation-of-three-urolithin-phenotypes-in-intervention-trials-independent-of-food-source-age-and-health-status\/\"><img loading=\"lazy\" class=\"alignleft size-full wp-image-2073\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/bacchus-other.png\" alt=\"bacchus other\" width=\"150\" height=\"100\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status<\/span><\/h3>\n<p>Francesco Tom\u00e1s-Barber\u00e1n and colleagues from CEBAS-CSIC(ES) have described three phenotypes for urolithin production, after intake of ellagitannin and ellagic acid. The proposed phenotypes could explain inter-individual variability &#8230; <strong><a href=\"http:\/\/www.bacchus-fp7.eu\/ellagic-acid-metabolism-by-human-gut-microbiota-consistent-observation-of-three-urolithin-phenotypes-in-intervention-trials-independent-of-food-source-age-and-health-status\/\">read more<\/a><\/strong><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/inhibition-of-vegf-signaling-by-polyphenols-in-relation-to-atherosclerosis-and-cardiovascular-disease-in-recent-advances-in-polyphenol-research\/\"><img loading=\"lazy\" class=\"alignleft wp-image-2039 size-full\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/06\/BacchusTea.png\" alt=\"Tea\" width=\"150\" height=\"100\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Inhibition of VEGF Signaling by Polyphenols in Relation to Atherosclerosis and Cardiovascular Disease in Recent Advances in Polyphenol Research<\/span><\/h3>\n<p>Rebecca Edwards and Paul Kroon with colleagues from the Institute of Food Research (UK) have reviewed the literature describing the potential for polyphenols to influence atherosclerosis &#8230; <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/inhibition-of-vegf-signaling-by-polyphenols-in-relation-to-atherosclerosis-and-cardiovascular-disease-in-recent-advances-in-polyphenol-research\/\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/bacchus-publications\/validated_method_pom\/\"><img loading=\"lazy\" class=\"alignleft wp-image-1969\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/06\/Pom.png\" alt=\"Pom\" width=\"150\" height=\"100\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Validated Method for the characterization and quantification of extractable and non-extractable ellagitannins after acid hydrolysis in pomegranate fruits, juices, and extracts<\/span><\/h3>\n<p>Rocio Garcia-Villalba and colleagues from CEBAS-CSIC (ES) have developed a new method for the analysis of the extractable and non-extractable ellagitannins, based on the quantification of acid hydrolysis products &#8230; <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/bacchus-publications\/validated_method_pom\/\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/nutrition-and-health-claims-in-practice\/\" target=\"_blank\"><img loading=\"lazy\" class=\"wp-image-1796 size-thumbnail alignleft\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/02\/Judy-Buttriss-150x150.jpg\" alt=\"\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Nutrition and health claims in practice<\/span><\/h3>\n<p>Judith Buttriss, Director General at the British Nutrition Foundation (UK) describes progress with implementation of the EU nutrition and health claims process, which covers all foods, drinks and dietary supplements sold in the EU and was established to ensure that claims about the nutritional or health attributes of products are substantiated by robust scientific evidence and can be relied upon by consumers\u00a0\u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/nutrition-and-health-claims-in-practice\/\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/the-cardiovascular-benefits-of-dark-chocolate\/\" target=\"_blank\"><img loading=\"lazy\" class=\"size-thumbnail wp-image-1658 alignleft\" src=\"\/wp-content\/uploads\/sites\/5\/2015\/12\/Chocolate-Image-150x150.png\" alt=\"Chocolate Image\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">The cardiovascular benefits of dark chocolate<\/span><\/h3>\n<p>Asimina Kerimi and Gary Williamson from the University of Leeds (UK) have found that human intervention studies analysing chocolate consumption are complicated by metabolic dysfunction amongst participants and limited molecular knowledge of flavanols. Their review concluded that future research on chocolate should focus on the effects of individual components on human health\u00a0\u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/?p=1657\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/?p=1623\" target=\"_blank\"><img loading=\"lazy\" class=\"alignleft size-thumbnail wp-image-1573\" src=\"\/wp-content\/uploads\/sites\/5\/2015\/11\/Legumes-Image-150x150.png\" alt=\"Legume Image\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Bioactive Peptides in Cereals and Legumes: Agronomical, Biochemical and Clinical Aspects<\/span><\/h3>\n<p>Arrigo F. G. Cicero and colleagues from the Departments of Life Quality Studies, Agricultural Sciences and Medicine and Surgery from Alma Mater Studiorum University of Bologna (IT) have conducted a review examining approaches for assessing effects of bioactive peptides from cereals and legumes. They determined that the best in vivo methods used activity-guided fractionation, where separation of protein-digested fractions is combined with an evaluation of specific biological activity in vivo\u00a0\u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/?p=1623\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/?p=1567\" target=\"_blank\"><img loading=\"lazy\" class=\"alignleft size-thumbnail wp-image-1573\" src=\"\/wp-content\/uploads\/sites\/5\/2015\/11\/Pomegranate-Image-150x150.png\" alt=\"Pomegranate Image\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients<\/span><\/h3>\n<p>Maria Nunez-Sanchez and colleagues from Quality, Safety and Bioactivity of Plant Foods (Campus de Espinardo, ES) and the Nutrition, Digestion, Surgery and Anatomical Pathology Services (Hospital Reina Sofia, Murcia, ES) found that colorectal cancer cells taken from patients who had consumed pomegranate extract (PE) contained bioactive polyphenols, such as ellagic acid (EA) and urolithins\u00a0\u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/?p=1567\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/?p=1539\" target=\"_blank\"><img loading=\"lazy\" class=\"alignleft size-thumbnail wp-image-1547\" src=\"\/wp-content\/uploads\/sites\/5\/2015\/11\/Wheat-Picture-150x150.png\" alt=\"Wheat Picture\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Lunasin in wheat: A chemical and molecular study on its presence or absence<\/span><\/h3>\n<p>Giovanni Dinelli and colleagues from Alma Mater Studiorum University of Bologna (IT), Bioaesis (IT) and Kamut International (USA) have confirmed there is no lunasin, nor any lunasin-like compound(s) with similar molecular weight(s), present in various wheat genotypes \u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/?p=1539\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/?p=1534\" target=\"_blank\"><img loading=\"lazy\" class=\"alignleft size-thumbnail wp-image-1549\" src=\"\/wp-content\/uploads\/sites\/5\/2015\/11\/Meat-Picture1-150x150.png\" alt=\"Meat Picture\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Optimisation of a simple and reliable label-free methodology for the relative quantitation of raw pork meat proteins<\/span><\/h3>\n<p>Marta Gallego and colleagues from Instituto de Agroqu\u00edmica y Tecnolog\u00eda de Alimentos (CSIC) (ES) have developed a rapid, simple, and reliable method to quantify changes in protein abundance in meat. This method will help identify bioactive proteins with potential health benefits. Proteomics is the study of the entire complement of proteins that is or can be expressed by a cell, tissue or organism \u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/?p=1534\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/?p=1402\" target=\"_blank\"><img loading=\"lazy\" class=\"alignleft wp-image-1643 size-thumbnail\" src=\"\/wp-content\/uploads\/sites\/5\/2015\/10\/Spanish-ham-Image-150x150.png\" alt=\"Spanish ham Image\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion<\/span><\/h3>\n<p>Elizabeth Escudero, Leticia Mora, Fidel Toldr\u00e1 from Instituto de Agroqu\u00edmica y Tecnolog\u00eda de Alimentos (CSIC, ES) have confirmed that peptides from dry-cured Designation of Origin of Teruel ham (D.O. Teruel, Spain) are stable after processing and digestion, and retain powerful Angiotensin I-converting enzyme (ACE) inhibitory activity.\u00a0Dietary proteins can help maintain or improve health following processing or digestion\u00a0\u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/?p=1402\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"http:\/\/www.bacchus-fp7.eu\/?p=1324\" target=\"_blank\"><img loading=\"lazy\" class=\"alignleft size-thumbnail wp-image-1335\" src=\"\/wp-content\/uploads\/sites\/5\/2015\/10\/apples_green_tea1-150x150.jpg\" alt=\"apples_green_tea\" width=\"150\" height=\"150\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Molecular structure-function relationship of dietary polyphenols for inhibiting VEGF-induced VEGFR-2<\/span><\/h3>\n<p>The Polyphenols and Health Group, led by Dr Paul Kroon, from the Institute of Food Research (UK), and Ana Cerezo from Nutrici\u00f3n y Bromatolog\u00eda, Facultad de Farmacia (Universidad de Sevilla, ES) have shown that some polyphenols bind directly with vascular endothelial growth factor (VEGF), which inhibits atherosclerosis and, therefore, progression of cardiovascular disease (CVD) \u2026 <span style=\"color: #339966\"><strong><a style=\"color: #339966\" href=\"http:\/\/www.bacchus-fp7.eu\/?p=1324\" target=\"_blank\">read more<\/a><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td>\u00a0<a href=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/Dry-ham.png\"><img loading=\"lazy\" class=\"alignleft wp-image-2082\" src=\"\/wp-content\/uploads\/sites\/5\/2016\/08\/Dry-ham.png\" alt=\"Dry ham\" width=\"150\" height=\"225\" \/><\/a><\/td>\n<td>\n<h3><span style=\"color: #339966\">Transepithelial transport of dry-cured ham peptides with ACE inhibitory activity through a Caco-2 cell monolayer<\/span><\/h3>\n<p>Marta Gallego and colleagues from the Instituto de Agroqu\u00edmica y Tecnolog\u00eda de Alimentos (CSIC, ES) and the Ghent University (BE) have examined the stability of naturally occurring angiotensin converting enzyme (ACE)-inhibitors in dry-cured ham during intestinal trans-epithelial transport using a Caco-2 cell monolayer&#8230;<a href=\"http:\/\/www.bacchus-fp7.eu\/transepithelial_dyecured_ham_peptides\/\"><strong>read more<\/strong><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table border=\"0\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<hr \/>\n<h2><span style=\"color: #339966\">Peer Reviewed Publications<\/span><\/h2>\n<p>Gonz\u00e1lez-Sarr\u00edas <em>et. al.<\/em> (2017), <strong>Clustering according to urolithin metabotype explains the interindividual variability in the improvement of cardiovascular risk biomarkers in overweight-obese individuals consuming pomegranate: A randomized clinical trial, <\/strong><em>Molecular Nutrition and Food Research, 2017, <\/em>DOI: 10.1002\/mnfr.201600830<u><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201600830\/abstract\">, http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201600830\/abstract<\/a><\/u><\/p>\n<p>Gonz\u00e1lez-Sarr\u00edas A. <em>et. al.<\/em> (2017), <strong>Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism, <\/strong><em>Eur J Nutr. 2017 Mar; 56(2): 831-841, <\/em>DOI: 10.1007\/s00394-015-1131-7-015-1131-7<u><a href=\"http:\/\/link.springer.com\/article\/10.1007%2Fs00394-015-1131-7\"> , http:\/\/link.springer.com\/article\/10.1007%2Fs00394-015-1131-7<\/a><\/u><\/p>\n<p>Gonz\u00e1lez-Sarr\u00edas A. <em>et. al.<\/em> (2017), <strong>Neuroprotective effects of bioavailable polyphenol-derived metabolites against oxidative stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells, <\/strong><em>J. Agric. Food Chem. 2017, 65, 752-758, <\/em>DOI: 10.1021\/acs.jafc.6b04538,\u00a0<u><a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.jafc.6b04538\"> http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.jafc.6b04538<\/a><\/u><\/p>\n<p>Kardum N. <em>et. al.<\/em> (2017), <strong>Design, formulation and sensory evaluation of a polyphenol-rich food placebo: an example of aronia juice for food intervention studies, <\/strong><em>International Journal of Food Sciences and Nutrition Published online: 01 Feb 2017, <\/em>Doi:10.1080\/09637486.2017.1283682<u>,http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/09637486.2017.1283682?journalCode=iijf20<\/u><\/p>\n<p>Selma M. V. <em>et. al.<\/em> (2017), <strong>The gut microbiota metabolism of pomegranate or walnut ellagitannins yields two main urolithin metabotypes that correlate with cardiometabolic risk biomarkers: comparison between normoweight, overweight-obese and metabolic syndrome subjects, <\/strong><em>Clinical Nutrition, 2017, <\/em><u><a href=\"http:\/\/www.clinicalnutritionjournal.com\/article\/S0261-5614(17)30103-6\/fulltext?rss=yes\">http:\/\/www.clinicalnutritionjournal.com\/article\/S0261-5614(17)30103-6\/fulltext?rss=yes<\/a><\/u><\/p>\n<p>Tumova S. <em>et. al.<\/em> (2017), <strong>Transendothelial glucose transport is not restricted by extracellular hyperglycaemia, <\/strong><em>Vascular Pharmacology, 2016, 87: 219-229, <\/em>http:\/\/dx.doi.org\/10.1016\/j.vph.2016.11.001, <a href=\"http:\/\/eprints.whiterose.ac.uk\/107240\/\">http:\/\/eprints.whiterose.ac.uk\/107240\/<\/a><\/p>\n<p>Van Rymenant E. <em>et. al.<\/em> (2017), <strong>Chronic exposure to short chain fatty acids modulates transport and metabolism of microbiome-derived phenolics in human intestinal cells, <\/strong><em>Journal of Nutritional Biochemistry, 2017, 39: 156-168<\/em>, <a href=\"http:\/\/www.jnutbio.com\/article\/S0955-2863(16)30399-0\/abstract\">http:\/\/www.jnutbio.com\/article\/S0955-2863(16)30399-0\/abstract<\/a><\/p>\n<p>Walker M. <em>et. al.<\/em> (2017), <strong>Health and nutrition claims \u2013 guidance, regulation and self-regulation, <\/strong><em>Nutrition Bulletin 2017, 42: 69-79, <\/em>doi:\u00a010.1111\/nbu.12251\u00a0 <u><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nbu.12251\/abstract\">\u00a0\u00a0\u00a0, http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nbu.12251\/abstract<\/a><\/u><\/p>\n<p>Kerimi A. <em>et. al.<\/em> (2016), <strong>At the interface of antioxidant signalling and cellular function: key polyphenol effects, <\/strong><em>Molecular Nutrition and Food Research, 60, 1770-1788, <\/em>DOI: 10.1002\/mnfr.201500940<u><a href=\"http:\/\/dx.doi.org\/10.1002\/mnfr.201500940\">, http:\/\/dx.doi.org\/10.1002\/mnfr.201500940<\/a><\/u><\/p>\n<p>Lucey A. <em>et. al.<\/em> (2016), <strong>Guidance for the design and implementation of human dietary intervention studies for health claim submissions, <\/strong><em>Nutrition Bulletin, accepted for publication , <\/em>DOI: 10.1111\/nbu.12241<u><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nbu.12241\/full\">, http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nbu.12241\/full<\/a><\/u><\/p>\n<p>Selma M. V. <em>et. al.<\/em> (2016), <strong>The human gut microbial ecology associated to overweight and obesity determines ellagic acid metabolism, <\/strong><em>Food &amp; Function, April 2016 7(4):1769-74, <\/em>DOI: 10.1039\/C5FO01100K<u><a href=\"http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2016\/FO\/C5FO01100K#!divAbstract\">, http:\/\/pubs.rsc.org\/en\/Content\/ArticleLanding\/2016\/FO\/C5FO01100K#!divAbstract<\/a><\/u><\/p>\n<p>Toldr\u00e1 F. <em>et. al.<\/em> (2016), <strong>Characterisation of the peptide profile of Spanish Teruel, Italian Parma and Belgian dry-cured hams and its potential bioactivity, <\/strong><em>Food Research International, 2016, 89, 638-646,<\/em><u><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0963996916304069\"> http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0963996916304069<\/a><\/u><\/p>\n<p>Toldr\u00e1 F. <em>et. al.<\/em> (2016), <strong>Peptidomics as a tool for quality control in dry-cured ham processing, <\/strong><em>Journal of Proteomics, 2016, 147, 98-107<\/em><u><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1874391916300422\"> http:\/\/www.sciencedirect.com\/science\/article\/pii\/S1874391916300422<\/a><\/u><\/p>\n<p>Tomas-Barberan F. A. <em>et. al.<\/em> (2016), <strong>Urolithins, the rescue of &#8216;old&#8217; metabolites to understand a &#8216;new&#8217; concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status, <\/strong><em>Molecular Nutrition and Food Research 2017, 61, 1, <\/em>DOI: 10.1002\/mnfr.201500901<u><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201500901\/abstract\">, http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201500901\/abstract<\/a><\/u><\/p>\n<p>Tomas-Barberan F. A. <em>et. al.<\/em> (2016), <strong>Interactions of gut microbiota with dietary polyphenols and consequences to human health, <\/strong><em>Curr. Opin. Clin. Nutr. Metab. Care, <\/em>DOI: 10.1097\/MCO.0000000000000314<u><a href=\"http:\/\/journals.lww.com\/co-clinicalnutrition\/pages\/articleviewer.aspx?year=2016&amp;issue=11000&amp;article=00012&amp;type=abstract\">, http:\/\/journals.lww.com\/co-clinicalnutrition\/pages\/articleviewer.aspx?year=2016&amp;issue=11000&amp;article=00012&amp;type=abstract<\/a><\/u><\/p>\n<p>Buttriss J. <em>et. al.<\/em> (2015), <strong>Nutrition and health claims in practice, <\/strong><em>Nutrition Bulletin, 40, 211\u2013222. , <\/em>DOI: 10.1111\/nbu.12155<u><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nbu.12155\/abstract\">, http:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/nbu.12155\/abstract<\/a><\/u><\/p>\n<p>Garcia-Villalba, R.\u00a0<em>et al.<\/em> (2015),\u00a0<strong>Validated method for the characterization and quantification of extractable and non-extractable ellagitannins after acid hydrolysis in pomegranate fruits, juices, and extracts,<\/strong>\u00a0<em>Agric. Food Chem.,<\/em>\u00a063(29): 6555\u20136566<\/p>\n<p>Gonzalez-Sarrias A.\u00a0<em>et al.<\/em> (2015),\u00a0<strong>Identifying the limits for ellagic acid bioavailability: a crossover pharmacokinetic study in healthy volunteers after consumption of pomegranate extracts,<\/strong>\u00a0<em>J. Functional Foods,<\/em>\u00a019: 225-235<\/p>\n<p>Grootaert C.\u00a0<em>et al.<\/em> (2015),\u00a0<strong>Cell Systems to Investigate the Impact of Polyphenols on Cardiovascular Health,<\/strong>\u00a0<em>Nutrients,<\/em>\u00a07: 1-28<\/p>\n<p>Kamiloglu S. <em>et. al.<\/em> (2015), <strong>Anthocyanin Absorption and Metabolism by Human Intestinal Caco-2 Cells &#8211; A Review, <\/strong><em>Int. J. Mol. Sci.\u00a02015,\u00a016(9), 21555-21574, <\/em>doi:10.3390\/ijms160921555<u><a href=\"http:\/\/www.mdpi.com\/1422-0067\/16\/9\/21555\">, http:\/\/www.mdpi.com\/1422-0067\/16\/9\/21555<\/a><\/u><\/p>\n<p>Kamiloglu S.\u00a0<em>et al.<\/em> (2015),\u00a0<strong>Anthocyanin Absorption and Metabolism by human Instestinal Caco-2 Cells &#8211; A Review,<\/strong>\u00a0<em>Int. J. Mol. Sci,<\/em>\u00a016(9): 21555-21574<\/p>\n<p>Kerimi A. <em>et. al.<\/em> (2015), <strong>The cardiovascular benefits of dark chocolate, <\/strong><em>Vascular Pharmacology, 2015, 71, Pages 11\u201315, <\/em>doi:10.1016\/j.vph.2015.05.011,<u><a href=\"https:\/\/doi.org\/10.1016\/j.vph.2015.05.011\">\u00a0 https:\/\/doi.org\/10.1016\/j.vph.2015.05.011<\/a><\/u><\/p>\n<p>Kronic Ristic A. <em>et. al.<\/em> (2015), <strong>Modulation of platelet function with dietary polyphenls &#8211; A promising strategy in the prevention of cardiovascular disease, <\/strong><em>Agro Food Industry Hi Tech; 2015;26(2):16-19, <\/em><a href=\"http:\/\/old.teknoscienze.com\/\/Contents\/Riviste\/Sfogliatore\/AF2_2015\/index.html#16\">http:\/\/old.teknoscienze.com\/\/Contents\/Riviste\/Sfogliatore\/AF2_2015\/index.html#16<\/a><\/p>\n<p>Mora L.\u00a0<em>et al.<\/em> (2015),\u00a0<strong>A peptidomic approach top study the contribution of added casein proteins to the peptides profile in Spanish dry-fermented sausages,<\/strong>\u00a0<em>International Journal of Food Microbiology (special issues for meat symposium),<\/em>\u00a0212: 41-48<\/p>\n<p>Romo-Vaquero M.\u00a0<em>et al.<\/em> (2015),\u00a0<strong>Interindividual variability in the human metabolism of ellagic acid: contribution of Gordonibacter to urolithin production,<\/strong>\u00a0<em>J. Functional Foods,<\/em>\u00a017: 785-791<\/p>\n<p>Cicero A. <em>et. al.<\/em> (2014), <strong>Bioactive peptides in cereals and legumes: Agronomical, biochemical and clinical aspects, <\/strong><em>Int J Mol Sci. 2014 Nov; 15(11): 21120\u201321135, <\/em>doi:\u00a0\u00a010.3390\/ijms151121120,<u><a href=\"https:\/\/dx.doi.org\/10.3390%2Fijms151121120\">\u00a0 https:\/\/dx.doi.org\/10.3390%2Fijms151121120<\/a><\/u><\/p>\n<p>Espin J. C. <em>et. al.<\/em> (2014), <strong>Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients, <\/strong><em>Molecular Nutrition and Food Research. Mol. Nutr. Food Res. 2014, 00, 1\u201313 Accepted Feburary 2014, <\/em>DOI: 10.1002\/mnfr.201300931<u><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0308814613018074\">, http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0308814613018074<\/a><\/u><\/p>\n<p>Kroon P. A. <em>et. al.<\/em> (2014), <strong>Potent inhibition of VEGFR-2 activation by tight binding of green tea epigallocatechin gallate and apple procyanidins to VEGF: Relevance to angiogenesis, <\/strong><em>Molecular Nutrition and Food Research. Mol. Nutr. <\/em><em>Food Res. 2015, 59, 401-412, <\/em>doi: 10.1002\/mnfr.201400478<u><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201400478\/abstract\">, http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mnfr.201400478\/abstract<\/a><\/u><\/p>\n<p>Toldr\u00e1 F. <em>et. al.<\/em> (2014), <strong>Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion, <\/strong><em>Food Chemistry, 2014, 161, 305-311, <\/em>doi:10.1016\/j.foodchem.2014.03.117,<u><a href=\"https:\/\/doi.org\/10.1016\/j.foodchem.2014.03.117\">\u00a0 https:\/\/doi.org\/10.1016\/j.foodchem.2014.03.117<\/a><\/u><\/p>\n<p>Tom\u00e1s-Barber\u00e1n F. A.\u00a0<em>et al.<\/em> (2014),\u00a0<strong>Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status,<\/strong>\u00a0<em>Agric. Food Chem.,<\/em>\u00a062(28): 6535-6538<\/p>\n<p>Edwards R. L.\u00a0<em>et al.<\/em> (2013),\u00a0<strong>Inhibition of VEGF signalling by polyphenols in relation to atherosclerosis and cardiovascular disease,<\/strong>\u00a0<em>Recent Advances in Polyphenol Research IV,<\/em>\u00a0DOI:\u00a010.1002\/9781118329634.ch9<\/p>\n<p>Dinelli G. <em>et. al.<\/em> (2013), <strong>Lunasin in wheat kernels: a chemical and molecular study on the absence or presence of the peptide, <\/strong><em>Available online 27th November 2013: Published Food Chemistry, Volume 151, 15 May 2014, Pages 520-525, <\/em>doi:10.1016\/j.foodchem.2013.11.119<u><a href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0308814613018074\">, http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0308814613018074<\/a><\/u><\/p>\n<p>Tom\u00e1s-Barber\u00e1n F. A.\u00a0<em>et al.<\/em> (2013),\u00a0<strong>Biological significance of urolithins, the Gut Microbial Ellagic Acid-derived metabolites: the evidence so far,<\/strong>\u00a0<em>Evidence-Based Complementary and Alternative Medicine,<\/em>\u00a02013: http:\/\/dx.doi.org\/10.1155\/2013\/270418<\/p>\n<p>Tom\u00e1s-Barber\u00e1n F. A.\u00a0<em>et al.<\/em> (2013),\u00a0<strong>Time Course Production of Urolithins from Ellagic acid by Human Gut Microbiota,<\/strong>\u00a0<em>Agric. Food Chem.,<\/em>\u00a061(37): 8797\u20138806<\/p>\n<hr \/>\n<h2><span style=\"color: #339966\">Book Chapter<\/span><\/h2>\n<p>Tomas-Barberan F. A. <em>et. al<\/em>.\u00a0 (2016), <strong>Gut microbiota metabolism, bioavailability and health benefits of pomegranate ellagitannins-derived urolithins, <\/strong><em>Pomegranate: Chemistry, Processing and Health, <\/em>ISBN 978-1-63485-687-4, <a href=\"https:\/\/www.novapublishers.com\/catalog\/product_info.php?products_id=59141&amp;osCsid=263867d043ef481530fa3926c86a39b3\">https:\/\/www.novapublishers.com\/catalog\/product_info.php?products_id=59141&amp;osCsid=263867d043ef481530fa3926c86a39b3<\/a><\/p>\n<hr \/>\n<h2><span style=\"color: #339966\">Other Dissemination Activities<\/span><\/h2>\n<p>Toldra F.\u00a0<em>et al.<\/em> (2015),\u00a0<strong>2nd International Symposium on Fermented Meat,<\/strong>\u00a0<em>Intl. J. Food Micro.,<\/em>\u00a0212: 1\u00a0<a id=\"ddDoi\" class=\"S_C_ddDoi\" href=\"http:\/\/dx.doi.org\/10.1016\/j.ijfoodmicro.2015.06.007\" target=\"doilink\">doi:10.1016\/j.ijfoodmicro.2015.06.007<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cell Systems to Investigate the Impact of Polyphenols on Cardiovascular Health Charlotte Grootaert and colleagues from Ghent (BE) and Istanbul Technical Universities (TR) have reviewed the literature concerning cell culture models for polyphenols and cardiovascular disease research &#8230;\u00a0read more Identifying the limits for ellagic acid bioavailability: A crossover pharmacokinetic study in healthy volunteers after consumption [&hellip;]<\/p>\n","protected":false},"author":38,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages\/1307"}],"collection":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/users\/38"}],"replies":[{"embeddable":true,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/comments?post=1307"}],"version-history":[{"count":90,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages\/1307\/revisions"}],"predecessor-version":[{"id":1580,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages\/1307\/revisions\/1580"}],"wp:attachment":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/media?parent=1307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}