
﻿{"id":2201,"date":"2016-09-13T12:53:52","date_gmt":"2016-09-13T11:53:52","guid":{"rendered":"http:\/\/www.bacchus-fp7.eu\/?page_id=2201"},"modified":"2016-09-13T14:43:10","modified_gmt":"2016-09-13T13:43:10","slug":"opc","status":"publish","type":"page","link":"http:\/\/www.eurofir.org\/bacchus\/opc\/","title":{"rendered":"OPC"},"content":{"rendered":"<p style=\"text-align: center;\"><strong>OPC Plus and the risk of chronic venous insufficiency<\/strong><\/p>\n<p>Read the following text and test your understanding on the questions below.<\/p>\n<p><strong>The application<\/strong><\/p>\n<p><span style=\"text-decoration: underline;\"><em>Proposed wording<\/em><\/span><\/p>\n<p>OPC improves venous microcirculation and increases capillary resistance and therefore may reduce the risk of chronic venous insufficiency.<\/p>\n<p><span style=\"text-decoration: underline;\"><em>Characterisation<\/em><\/span><\/p>\n<p>The product is a grape seed extract described as containing 40 mg oligomeric procyanidins (OPC), 40 mg berry-blend per capsule and inulin (338 mg). The manufacturing process has been described.\u00a0 No information was provided on the berry blend.<\/p>\n<p><span style=\"text-decoration: underline;\"><em>Beneficial effect<\/em><\/span><\/p>\n<p>Improvement of venous microcirculation and increases capillary resistance and therefore reduction of risk of chronic venous insufficiency.<\/p>\n<p><span style=\"text-decoration: underline;\"><em>Scientific substantiation<\/em><\/span><\/p>\n<p>20 references were provided as being pertinent to the claimed effect. No details concerning the search strategy were provided.\u00a0No human intervention studies using the OPC were provided.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Question 1<\/strong><\/p>\n<p>Do you see the benefit in putting this claim on a product?<\/p>\n<p><em>Correct answer:<\/em> <div id=\"b-link-2201\" class=\"sh-link b-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('b', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"b-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"b-content-2201\" class=\"sh-content b-content sh-hide\" style=\"display: none;\"><strong>Yes<\/strong><\/div><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Question 2<\/strong><\/p>\n<p>Why?<\/p>\n<p><em>Correct answer:<\/em> <div id=\"bc-link-2201\" class=\"sh-link bc-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('bc', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"bc-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"bc-content-2201\" class=\"sh-content bc-content sh-hide\" style=\"display: none;\"><strong>This health claim may appeal to those at risk of chronic venous insufficiency<\/strong><\/div><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Question 3<\/strong><\/p>\n<p>Do you think consumers would understand the wording of the claim?<\/p>\n<p><em>Correct answer:<\/em> <div id=\"bcd-link-2201\" class=\"sh-link bcd-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('bcd', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"bcd-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"bcd-content-2201\" class=\"sh-content bcd-content sh-hide\" style=\"display: none;\"><strong>No<\/strong><\/div><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Question 4<\/strong><\/p>\n<p>Why?<\/p>\n<p><em>Correct answer:<\/em> <div id=\"bcde-link-2201\" class=\"sh-link bcde-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('bcde', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"bcde-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"bcde-content-2201\" class=\"sh-content bcde-content sh-hide\" style=\"display: none;\"><strong>This health claim includes scientific wording, which may cause confusion to the average consumer.<\/strong><\/div><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Question 5<\/strong><\/p>\n<p>What do you understand by \u2018characterisation\u2019 in this case? (i.e. What is it in the component of the product that has been identified as having the health effect and has this been sufficiently characterised?)<\/p>\n<p><em>Correct answer:<\/em> <div id=\"bcdef-link-2201\" class=\"sh-link bcdef-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('bcdef', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"bcdef-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"bcdef-content-2201\" class=\"sh-content bcdef-content sh-hide\" style=\"display: none;\"><strong>The food, OPC Plus, which is the subject of the health claim, is sufficiently characterised with respect to OPC extracted from grapes.<\/strong><\/div><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Question 6<\/strong><\/p>\n<p>Do you agree that the effect in question is likely to be beneficial for the general population?<\/p>\n<p><em>Correct answer:<\/em> <div id=\"bcdefg-link-2201\" class=\"sh-link bcdefg-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('bcdefg', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"bcdefg-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"bcdefg-content-2201\" class=\"sh-content bcdefg-content sh-hide\" style=\"display: none;\"><strong>Yes, the claim brings some confusion &#8211; alterations in the venous microcirculation (i.e., venous microangiopathy) is a consequence rather than a cause of (or a risk factor for) chronic venous insufficiency and as such, improving the \u201calterations\u201d in the venous microcirculation is not classed as a beneficial physiological effect.<\/strong><\/div><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Question 7<\/strong><\/p>\n<p>What do you think about the level of evidence provided for the scientific substantiation?<\/p>\n<p>You could consider:<\/p>\n<ol>\n<li>Were randomized controlled trials (RCTs) in humans included<\/li>\n<li>Were the studies performed with the product\/compound of interest?<\/li>\n<li>Were the measures of the health effect valid?<\/li>\n<li>Was there a dose-response relationship?<\/li>\n<li>Was there evidence provided for a mechanism by which the product\/component has the effect?<\/li>\n<\/ol>\n<p><em>Correct answer:<\/em><\/p>\n<div id=\"bcdefgh-link-2201\" class=\"sh-link bcdefgh-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('bcdefgh', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"bcdefgh-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"bcdefgh-content-2201\" class=\"sh-content bcdefgh-content sh-hide\" style=\"display: none;\"><strong>No human intervention studies using the constituent OPC extracted from grape were provided.<\/strong><\/div>\n<p>&nbsp;<\/p>\n<p><strong>Question 8<\/strong><\/p>\n<p>Do you think the claim was given a positive opinion?<\/p>\n<p><em>Correct answer:<\/em> <div id=\"bcdefghi-link-2201\" class=\"sh-link bcdefghi-link sh-hide\"><a href=\"#\" onclick=\"showhide_toggle('bcdefghi', 2201, 'Show Answer', ''); return false;\" aria-expanded=\"false\"><span id=\"bcdefghi-toggle-2201\">Show Answer<\/span><\/a><\/div><div id=\"bcdefghi-content-2201\" class=\"sh-content bcdefghi-content sh-hide\" style=\"display: none;\"><strong>No, the EFSA panel concluded that a cause and effect relationship has not been established between the consumption of OPC Plus and reducing the risk of chronic venous insufficiency by increasing microcirculation.<\/strong><\/div><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>OPC Plus and the risk of chronic venous insufficiency Read the following text and test your understanding on the questions below. The application Proposed wording OPC improves venous microcirculation and increases capillary resistance and therefore may reduce the risk of chronic venous insufficiency. Characterisation The product is a grape seed extract described as containing 40 [&hellip;]<\/p>\n","protected":false},"author":4708,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages\/2201"}],"collection":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/users\/4708"}],"replies":[{"embeddable":true,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/comments?post=2201"}],"version-history":[{"count":3,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages\/2201\/revisions"}],"predecessor-version":[{"id":2222,"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/pages\/2201\/revisions\/2222"}],"wp:attachment":[{"href":"http:\/\/www.eurofir.org\/bacchus\/wp-json\/wp\/v2\/media?parent=2201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}